Search results for " Experimental characterization"
showing 2 items of 2 documents
Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum
2019
Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could be a useful replacement for protamine, which is in current clinical use. However, micelles can have low stability in human serum and unacceptable toxicity profiles. This paper reports the optimi- sation of self-assembled multivalent (SAMul) arrays of amphiphilic ligands to bind heparin in competitive conditions. Specifically, modification of the hydrophobic unit kinetically stabilises the self-assembled nanostructures, preventing loss of binding ability in the presence of…
DACRON© 360 WOVEN: EXPERIMENTAL CHARACTERIZATION AND COMPUTATIONAL ASPECTS
2010
In this paper a first experimental study on Dacron© 360 woven constitutive behavior is presented. This woven is widely adopted in sail manufacturing, it is obtained by weaving polyethylene terephthalate (PET) yarn and it shows some peculiar features due to its own manufacturing process. The experimental tests, in terms of tensile tests and cyclic tests, clearly show the orthotropy features of the material, its high strength and deformability. The examination with optical microscope of the tested specimen allows to evidence the interaction between warp and weft yarns. The obtained results represent a first step for the definition of a correct computational approach to such materials.